Peru have clinched the South American play-off spot in their bid to qualify for Qatar 2022, while Brazil broke Argentina's points record in their victory over Bolivia.
Vinicius Junior celebrated a return to the Maracana stadium with his first international goal for Brazil and a starring performance in their 4-0 thrashing of Chile.
Raphina and Philippe Coutinho inspire Brazil to Paraguay win, Argentina dent Colombia's hopes; plus: Rodrigo Bentancur and Alexis Sanchez on target.
Chile saw their chances of qualifying for the 2022 World Cup shrink dramatically after a 2-1 home defeat to second-place Argentina.
Brazil moved within one win of qualifying for next year's World Cup by thrashing Uruguay 4-1 in Manaus, with Leeds' Raphinha scoring twice.
Blackburn have reached an agreement with the Chilean football federation over the release of Ben Brereton Diaz in the October international break.