The Copa del Rey derby match between Real Betis and Sevilla was suspended after a pole hurled from the stands hit Sevilla player Joan Jordan in the head on Saturday.
La Liga champions Atletico Madrid were stunned by Granada, losing 2-1 on Wednesday, while Napoli slipped to defeat against Spezia in Serie A.
Serie A leaders Napoli lost for the first time this season as Inter Milan reinvigorated their own title bid with a 3-2 win at the San Siro.
Bayern Munich thrashed Bayer Leverkusen 5-1 to reclaim top spot in the Bundesliga, while Juventus continued their winning run by beating Jose Mourinho's Roma.
The disciplinary committee of the French League (LFP) will meet on Monday after crowd trouble marred Saturday's Ligue 1 clash between Lens and Lille.
Przemyslaw Frankowski earned Lens their first victory over Lille for 15 years in a derby marred by crowd trouble, while Bayern Munich and Inter both racked up big wins.